Inverting the selectivity of aquaporin 6: Gating versus direct electrostatic interaction

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Inverting the selectivity of aquaporin 6: gating versus direct electrostatic interaction.

S pecialized transmembrane proteins form channels that facilitate the transport of ions and other molecules across the membranes and thus play crucial role in many life processes. The understanding of these systems has increased enormously in recent years because of advances in structural and biochemical studies (e.g., refs. 1 and 2). However, key questions remain with regards to the exact fact...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2005

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0409788102